Topical chemotherapy works by modifying the body’s immune response. This means it leverages the body’s own immune response or natural defenses to do its work. When this topical solution is applied to the skin, it acts locally, triggering the release of cytokines, such as interferon. These substances then work to kill any virus present on the skin that is causing a condition. It can also target abnormal skin cells that happen from some cancers and with keratoses.
Topical chemotherapy is used to treat actinic keratosis on the face and scalp. It is also used to treat minor forms of skin cancer, such as basal cell carcinoma, when surgery is not the best option in terms of treatment. Topical chemotherapy creams include Aldara, Carac and Efudex. Side effects can include irritation at the site of treatment and sensitivity to UV light.
Topical chemotherapy is used to treat actinic keratosis on the face and scalp. It is also used to treat minor forms of skin cancer, such as basal cell carcinoma, when surgery is not the best option in terms of treatment. Topical chemotherapy creams include Aldara, Carac and Efudex. Side effects can include irritation at the site of treatment and sensitivity to UV light.
Most patients do not experience significant pain from topical chemotherapy itself, but the treated area may become red, irritated, tender, or sensitive as abnormal cells respond to the medication. The severity of these reactions varies based on the medication used and the treatment area.
Common side effects may include redness, inflammation, scaling, crusting, itching, burning, and temporary skin sensitivity. These reactions are often expected because the medication is targeting abnormal or precancerous cells within the treatment area.
During treatment, the skin may become red, irritated, scaly, or crusted as damaged cells are destroyed. The appearance and severity of the reaction can vary depending on the treatment plan, medication strength, and individual response.
Patients are often advised to limit sun exposure and follow their dermatologist’s instructions regarding skincare products and other topical treatments. Specific recommendations may vary depending on the medication being used and the condition being treated.
Topical chemotherapy may be recommended for certain superficial skin cancers, precancerous lesions such as actinic keratoses, or areas of extensive sun damage. Your dermatologist will determine whether topical treatment or another treatment approach is most appropriate based on the diagnosis and treatment goals.
